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NGS in clinical diagnostics

NGS validation as a service

NGS validation as a service

Every clinical lab is facing challenges when validating NGS assays. An automated validation process on the varvis® platform make this as…
Go to the profile of Ben Liesfeld
Ben Liesfeld
Should we sequence at 2x150 or 2x100 cycles?

Should we sequence at 2x150 or 2x100 cycles?

Once and again we are asked about the pros and cons of paired-end sequencing at different read lengths. In this article, we will quantify…
Go to the profile of Ben Liesfeld
Ben Liesfeld
CNV analysis from NGS compared to PCR based methods

CNV analysis from NGS compared to PCR based methods

We are asked quite often these days how CNV analysis from NGS data compares to the gold standard method which is based on…
Go to the profile of Ben Liesfeld
Ben Liesfeld
Is confirmation of NGS results by Sanger sequencing still required?

Is confirmation of NGS results by Sanger sequencing still required?

A question that is frequently asked in clinical diagnostics is:
Go to the profile of Ben Liesfeld
Ben Liesfeld
Selecting the right reference samples for SNV validation

Selecting the right reference samples for SNV validation

Regulations and guidelines demand that clinical processes are validated. Since Limbus provides NGS validation reports as a service, our…
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Samuel
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